Xanax has a half-life ranging from 6.3 to 26.9 hours in adults who are in good health, according to the U.S. Food & Drug Administration. Half-life refers to the amount of time it takes for the user’s body to metabolize approximately half of the substance. Due to its relatively short half-life, the initial Xanax detoxification period typically lasts for four to five days, but it takes up to a week in some users.
The full withdrawal phase usually takes several weeks, but it can take up to a full year depending on the user’s health status and how long the user has been taking Xanax. Other factors that affect the length of the withdrawal process include how much Xanax the user has been taking and whether the user has been taking Xanax in combination with other substances. A user who has been taking Xanax for several years is likely to need more time to complete the detoxification process than someone who has been using Xanax for only a few months.
Withdrawal Symptoms
Xanax Withdrawal Symptoms
Severe physical symptoms sometimes occur during the Xanax detoxification process
Seizures can occur in users who stop using Xanax suddenly instead of going through a monitored medical detoxification process. In a study on the management of seizures caused by benzodiazepine withdrawal, Hu discovered that seizures can occur after as little as 15 days of benzodiazepine use. Therefore, it is safer for users to withdraw from Xanax under the supervision of medical professionals rather than withdrawing from the substance on their own.
Xanax withdrawal can lead to suicidal thoughts and other severe psychological effects
In some users, Xanax can lead to disinhibition, which causes an altered mental state characterized by impulsivity. Some of these users may have suicidal thoughts while they are withdrawing from Xanax. The risk of suicidal thoughts increases when Xanax is used with alcohol, illicit drugs, and some other prescription medications.
Xanax withdrawal can lead to sudden death
Lann and Molina reported on a case of sudden death that occurred when a user suddenly switched from one benzodiazepine to another. The user developed a fever, high blood pressure, bizarre behavior, and seizure activity. Approximately 15 hours after being admitted to the hospital, the user died unexpectedly. Her death was attributed to the fact that she switched to a different substance without tapering the dose of the first one.
Xanax Detoxification Medications
In some cases, medications are used to ease the physical discomfort and psychological symptoms that can occur during Xanax detoxification. Long-acting benzodiazepines, which have a longer half-life than Xanax, may be prescribed to help the user avoid withdrawal symptoms. Some users take antidepressants to help them with the depression that may develop during the withdrawal process. For users experiencing seizures, barbiturates may be used to control seizure activity.
For more information about withdrawal, read our guide on Xanax Addiction.